If you're wondering what to do with a large fully cooked thick slice of ham, there are countless delicious options to consider. You can slice it up for sandwiches, dice it for salads or soups, or even chop it up for a hearty pasta dish. You could also consider using it as a main dish, perhaps glazing it with a sweet or spicy sauce. Think outside the box and use it in a breakfast scramble or as a pizza topping. The possibilities are endless with this versatile protein staple.